View source for 2mwe


==NMR structure of FBP28 WW2 mutant Y438R, L453A DNDC==
<StructureSection load='2mwe' size='340' side='right'caption='[[2mwe]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2mwe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MWE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MWE FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mwe OCA], [https://pdbe.org/2mwe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mwe RCSB], [https://www.ebi.ac.uk/pdbsum/2mwe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mwe ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TCRG1_HUMAN TCRG1_HUMAN] Transcription factor that binds RNA polymerase II and inhibits the elongation of transcripts from target promoters. Regulates transcription elongation in a TATA box-dependent manner. Necessary for TAT-dependent activation of the human immunodeficiency virus type 1 (HIV-1) promoter.<ref>PMID:9315662</ref> <ref>PMID:11604498</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Macias MJ]]
[[Category: Scheraga H]]
[[Category: Sunol D]]
[[Category: Todorovski T]]