View source for 2poe


==Crystal structure of Cryptosporidium parvum cyclophilin type peptidyl-prolyl cis-trans isomerase cgd2_1660==
<StructureSection load='2poe' size='340' side='right'caption='[[2poe]], [[Resolution|resolution]] 2.01&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2poe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptosporidium_parvum_Iowa_II Cryptosporidium parvum Iowa II]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2POE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2POE FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.01&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2poe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2poe OCA], [https://pdbe.org/2poe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2poe RCSB], [https://www.ebi.ac.uk/pdbsum/2poe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2poe ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A3FQ68_CRYPI A3FQ68_CRYPI] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.[RuleBase:RU004223]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/po/2poe_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2poe ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Cryptosporidium parvum Iowa II]]
[[Category: Large Structures]]
[[Category: Amani M]]
[[Category: Arrowsmith CH]]
[[Category: Artz JD]]
[[Category: Bochkarev A]]
[[Category: Edwards AM]]
[[Category: Hassanali A]]
[[Category: Hills T]]
[[Category: Hui R]]
[[Category: Kozieradzki I]]
[[Category: Lew J]]
[[Category: Lin L]]
[[Category: Schapira M]]
[[Category: Sundstrom M]]
[[Category: Vedadi M]]
[[Category: Wasney G]]
[[Category: Weigelt J]]
[[Category: Wernimont AK]]
[[Category: Zhao Y]]