View source for 2ru1


==Solution structure of esf3==
<StructureSection load='2ru1' size='340' side='right'caption='[[2ru1]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2ru1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RU1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RU1 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ru1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ru1 OCA], [https://pdbe.org/2ru1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ru1 RCSB], [https://www.ebi.ac.uk/pdbsum/2ru1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ru1 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ESF13_ARATH ESF13_ARATH] Maternally-contributed central cell peptide regulating suspensor development and correct auxin distribution in early developing embryos.<ref>PMID:24723605</ref> 
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Plant embryogenesis initiates with the establishment of an apical-basal axis; however, the molecular mechanisms accompanying this early event remain unclear. Here, we show that a small cysteine-rich peptide family is required for formation of the zygotic basal cell lineage and proembryo patterning in Arabidopsis. EMBRYO SURROUNDING FACTOR 1 (ESF1) peptides accumulate before fertilization in central cell gametes and thereafter in embryo-surrounding endosperm cells. Biochemical and structural analyses revealed cleavage of ESF1 propeptides to form biologically active mature peptides. Further, these peptides act in a non-cell-autonomous manner and synergistically with the receptor-like kinase SHORT SUSPENSOR to promote suspensor elongation through the YODA mitogen-activated protein kinase pathway. Our findings demonstrate that the second female gamete and its sexually derived endosperm regulate early embryonic patterning in flowering plants.

Central cell-derived peptides regulate early embryo patterning in flowering plants.,Costa LM, Marshall E, Tesfaye M, Silverstein KA, Mori M, Umetsu Y, Otterbach SL, Papareddy R, Dickinson HG, Boutiller K, VandenBosch KA, Ohki S, Gutierrez-Marcos JF Science. 2014 Apr 11;344(6180):168-72. doi: 10.1126/science.1243005. PMID:24723605<ref>PMID:24723605</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 2ru1" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Large Structures]]
[[Category: Mori M]]
[[Category: Ohki S]]
[[Category: Umetsu Y]]