View source for 2w21


==Crystal structure of the aminoacid kinase domain of the glutamate 5 kinase of Escherichia coli.==
<StructureSection load='2w21' size='340' side='right'caption='[[2w21]], [[Resolution|resolution]] 2.95&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2w21]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_BL21 Escherichia coli BL21]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W21 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W21 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.95&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w21 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w21 OCA], [https://pdbe.org/2w21 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w21 RCSB], [https://www.ebi.ac.uk/pdbsum/2w21 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w21 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PROB_ECOLI PROB_ECOLI] Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.[HAMAP-Rule:MF_00456]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w2/2w21_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2w21 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Escherichia coli BL21]]
[[Category: Large Structures]]
[[Category: Cervera J]]
[[Category: Gil-Ortiz F]]
[[Category: Marco-Marin C]]
[[Category: Perez-Arellano I]]
[[Category: Rubio V]]