View source for 2wgl


==Crystal structure of Helicobactor pylori UreF==
<StructureSection load='2wgl' size='340' side='right'caption='[[2wgl]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2wgl]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WGL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WGL FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wgl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wgl OCA], [https://pdbe.org/2wgl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wgl RCSB], [https://www.ebi.ac.uk/pdbsum/2wgl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wgl ProSAT]</span></td></tr>
</table>
== Function ==
[[https://www.uniprot.org/uniprot/UREF_HELPY UREF_HELPY]] Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity).[HAMAP-Rule:MF_01385] 
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wg/2wgl_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wgl ConSurf].
<div style="clear:both"></div>

==See Also==
*[[Urease accessory protein|Urease accessory protein]]
__TOC__
</StructureSection>
[[Category: Helicobacter pylori]]
[[Category: Large Structures]]
[[Category: Chen, Y W]]
[[Category: Fong, Y H]]
[[Category: Wong, K B]]
[[Category: Chaperone]]
[[Category: Cytoplasm]]
[[Category: Metal binding protein]]
[[Category: Nickel insertion]]
[[Category: Virulence]]