View source for 2wna


==Crystal structure of the GNA 3'-G(Br)CGCGC-2'==
<StructureSection load='2wna' size='340' side='right'caption='[[2wna]], [[Resolution|resolution]] 0.97&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2wna]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WNA FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.97&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene>, <scene name='pdbligand=ZBC:(2S)-3-(4-AMINO-5-BROMO-2-OXOPYRIMIDIN-1(2H)-YL)-2-HYDROXYPROPYL+DIHYDROGEN+PHOSPHATE'>ZBC</scene>, <scene name='pdbligand=ZCY:(S)-1-(2,3-DIHYDROXYPROPYL)-CYTOSINE'>ZCY</scene>, <scene name='pdbligand=ZGU:(S)-1-(2,3-DIHYDROXYPROPYL)-GUANINE'>ZGU</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wna FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wna OCA], [https://pdbe.org/2wna PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wna RCSB], [https://www.ebi.ac.uk/pdbsum/2wna PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wna ProSAT]</span></td></tr>
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Double helix variations of glycol nucleic acids (GNA) are revealed by the atomic resolution crystal structure of a 6mer GNA duplex containing solely Watson-Crick type hydrogen-bonded base pairs.

Atomic resolution duplex structure of the simplified nucleic acid GNA.,Schlegel MK, Essen LO, Meggers E Chem Commun (Camb). 2010 Feb 21;46(7):1094-6. Epub 2009 Dec 21. PMID:20126724<ref>PMID:20126724</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 2wna" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Essen L-O]]
[[Category: Meggers E]]
[[Category: Schlegel MK]]