View source for 2wzr


==The Structure of Foot and Mouth Disease Virus Serotype SAT1==
<StructureSection load='2wzr' size='340' side='right'caption='[[2wzr]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2wzr]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Foot-and-mouth_disease_virus_SAT_1 Foot-and-mouth disease virus SAT 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WZR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WZR FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wzr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wzr OCA], [https://pdbe.org/2wzr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wzr RCSB], [https://www.ebi.ac.uk/pdbsum/2wzr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wzr ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q6PMU1_9PICO Q6PMU1_9PICO] Protein 3C is a cysteine protease that generates mature viral proteins from the precursor polyprotein. In addition to its proteolytic activity, it binds to viral RNA, and thus influences viral genome replication. RNA and substrate bind co-operatively to the protease (By similarity).  RNA-directed RNA polymerase 3D-POL replicates genomic and antigenomic RNA by recognizing replications specific signals (By similarity).[SAAS:SAAS001676_004_010047]
__TOC__
</StructureSection>
[[Category: Foot-and-mouth disease virus SAT 1]]
[[Category: Large Structures]]
[[Category: Adams P]]
[[Category: Blakemore W]]
[[Category: Fry E]]
[[Category: King A]]
[[Category: Lea S]]
[[Category: Newman J]]
[[Category: Stuart D]]