View source for 2xu5


==CATHEPSIN L WITH A NITRILE INHIBITOR==
<StructureSection load='2xu5' size='340' side='right'caption='[[2xu5]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2xu5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XU5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XU5 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=XU5:(2S,4R)-4-(2-CHLOROPHENYL)SULFONYL-N-[1-(IMINOMETHYL)CYCLOPROPYL]-1-[1-(4-METHYLPHENYL)CYCLOPROPYL]CARBONYL-PYRROLIDINE-2-CARBOXAMIDE'>XU5</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xu5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xu5 OCA], [https://pdbe.org/2xu5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xu5 RCSB], [https://www.ebi.ac.uk/pdbsum/2xu5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xu5 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CATL1_HUMAN CATL1_HUMAN] Important for the overall degradation of proteins in lysosomes.

==See Also==
*[[Cathepsin 3D structures|Cathepsin 3D structures]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Banner DW]]
[[Category: Benz JM]]
[[Category: Haap W]]