View source for 2yiz


==X-ray structure of Mycobacterium tuberculosis Dodecin==
<StructureSection load='2yiz' size='340' side='right'caption='[[2yiz]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2yiz]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YIZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YIZ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yiz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yiz OCA], [https://pdbe.org/2yiz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yiz RCSB], [https://www.ebi.ac.uk/pdbsum/2yiz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yiz ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q8VK10_MYCTO Q8VK10_MYCTO] 
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== Publication Abstract from PubMed ==
The suitability for chemical engineering of the highly symmetrical Mycobacterium tuberculosis dodecin was investigated, its inner cavity providing a large compartment shields introduced compounds from bulk solvent. Hybrids were obtained by S-alkylation of cysteine mutants and characterized by spectroscopic methods, including the crystal structures of wild type and biohybrid dodecins.

Chemical engineering of Mycobacterium tuberculosis dodecin hybrids.,Vinzenz X, Grosse W, Linne U, Meissner B, Essen LO Chem Commun (Camb). 2011 Oct 21;47(39):11071-3. Epub 2011 Sep 6. PMID:21897938<ref>PMID:21897938</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 2yiz" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Essen L-O]]
[[Category: Grosse W]]
[[Category: Linne U]]
[[Category: Meissner B]]
[[Category: Vinzenz X]]