View source for 2yre


==Solution structure of the zinc finger domains (1-87) from human F-box only protein==
<StructureSection load='2yre' size='340' side='right'caption='[[2yre]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2yre]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YRE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YRE FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yre FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yre OCA], [https://pdbe.org/2yre PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yre RCSB], [https://www.ebi.ac.uk/pdbsum/2yre PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yre ProSAT], [https://www.topsan.org/Proteins/RSGI/2yre TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FBX30_HUMAN FBX30_HUMAN] Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yr/2yre_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2yre ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Hayashi F]]
[[Category: Nagashima T]]
[[Category: Suetake T]]
[[Category: Yokoyama S]]