View source for 2zsh


==Structural basis of gibberellin(GA3)-induced DELLA recognition by the gibberellin receptor==
<StructureSection load='2zsh' size='340' side='right'caption='[[2zsh]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2zsh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZSH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZSH FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GA3:GIBBERELLIN+A3'>GA3</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zsh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zsh OCA], [https://pdbe.org/2zsh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zsh RCSB], [https://www.ebi.ac.uk/pdbsum/2zsh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zsh ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GID1A_ARATH GID1A_ARATH] Functions as soluble gibberellin (GA) receptor. GA is an essential hormone that regulates growth and development in plants. Binds with high affinity the biologically active gibberellin GA4, but has no affinity for the biologically inactive GAs. In response to GA, interacts with specific DELLA proteins, known as repressors of GA-induced growth, and targets them for degradation via proteasome. Seems to be required for GA signaling that controls root growth, seed germination, stem elongation and flower development. Partially redundant with GID1B and GID1C.<ref>PMID:16709201</ref> <ref>PMID:17194763</ref> <ref>PMID:17521411</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Large Structures]]
[[Category: Hakoshima T]]
[[Category: Hirano Y]]
[[Category: Murase K]]
[[Category: Sun TP]]