View source for 3ae3


==Crystal structure of porcine heart mitochondrial complex II bound with 2-Nitro-N-phenyl-benzamide==
<StructureSection load='3ae3' size='340' side='right'caption='[[3ae3]], [[Resolution|resolution]] 3.35&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3ae3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AE3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AE3 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.35&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPH:L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINE'>EPH</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=NBI:2-NITRO-N-PHENYLBENZAMIDE'>NBI</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ae3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ae3 OCA], [https://pdbe.org/3ae3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ae3 RCSB], [https://www.ebi.ac.uk/pdbsum/3ae3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ae3 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SDHA_PIG SDHA_PIG] Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Can act as a tumor suppressor (By similarity).

==See Also==
*[[Succinate dehydrogenase 3D structures|Succinate dehydrogenase 3D structures]]
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</StructureSection>
[[Category: Large Structures]]
[[Category: Sus scrofa]]
[[Category: Harada S]]
[[Category: Honma T]]
[[Category: Inaoka DK]]
[[Category: Inoue M]]
[[Category: Kido Y]]
[[Category: Kita K]]
[[Category: Mao J]]
[[Category: Matsuoka S]]
[[Category: Omori J]]
[[Category: Osanai A]]
[[Category: Sakamoto K]]
[[Category: Sasaki T]]
[[Category: Shindo M]]
[[Category: Tanaka A]]