View source for 3ai8


==Cathepsin B in complex with the nitroxoline==
<StructureSection load='3ai8' size='340' side='right'caption='[[3ai8]], [[Resolution|resolution]] 2.11&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3ai8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AI8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AI8 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.11&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HNQ:5-NITROQUINOLIN-8-OL'>HNQ</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ai8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ai8 OCA], [https://pdbe.org/3ai8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ai8 RCSB], [https://www.ebi.ac.uk/pdbsum/3ai8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ai8 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CATB_HUMAN CATB_HUMAN] Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.

==See Also==
*[[Cathepsin|Cathepsin]]
*[[Cathepsin 3D structures|Cathepsin 3D structures]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Gobec S]]
[[Category: Kos J]]
[[Category: Mirkovic B]]
[[Category: Renko M]]
[[Category: Turk D]]