View source for 3aqo


==Structure and function of a membrane component SecDF that enhances protein export==
<StructureSection load='3aqo' size='340' side='right'caption='[[3aqo]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3aqo]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AQO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AQO FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3aqo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3aqo OCA], [https://pdbe.org/3aqo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3aqo RCSB], [https://www.ebi.ac.uk/pdbsum/3aqo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3aqo ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SECDF_THET8 SECDF_THET8] Conducts protons, which can be regulated by a proton gradient or by binding of an unfolded protein. Proton conduction requires the large periplasmic domain of the SecD.[HAMAP-Rule:MF_01463_B]  Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.[HAMAP-Rule:MF_01463_B]
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</StructureSection>
[[Category: Large Structures]]
[[Category: Thermus thermophilus HB8]]
[[Category: Echizen Y]]
[[Category: Ishitani R]]
[[Category: Nureki O]]
[[Category: Tsukazaki T]]