View source for 3ay5


==Crystal structure of HHM (human homologue of murine maternal Id-like molecule)==
<StructureSection load='3ay5' size='340' side='right'caption='[[3ay5]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3ay5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AY5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AY5 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ay5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ay5 OCA], [https://pdbe.org/3ay5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ay5 RCSB], [https://www.ebi.ac.uk/pdbsum/3ay5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ay5 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CCDB1_HUMAN CCDB1_HUMAN] May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription.<ref>PMID:10801854</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Ishitani R]]
[[Category: Nureki O]]
[[Category: Seto A]]