View source for 3brq


==Crystal structure of the Escherichia coli transcriptional repressor ascG==
<StructureSection load='3brq' size='340' side='right'caption='[[3brq]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3brq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BRQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BRQ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FRU:FRUCTOSE'>FRU</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ascG, b2714, JW5434 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3brq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3brq OCA], [https://pdbe.org/3brq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3brq RCSB], [https://www.ebi.ac.uk/pdbsum/3brq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3brq ProSAT], [https://www.topsan.org/Proteins/MCSG/3brq TOPSAN]</span></td></tr>
</table>
== Function ==
[[https://www.uniprot.org/uniprot/ASCG_ECOLI ASCG_ECOLI]] Repressor of the asc operon. The cryptic operon is activated by the insertion of IS186 into the ascG gene. 
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/br/3brq_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3brq ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Ecoli]]
[[Category: Large Structures]]
[[Category: Edwards, A M]]
[[Category: Evdokimova, E]]
[[Category: Joachimiak, A]]
[[Category: Kagan, O]]
[[Category: Structural genomic]]
[[Category: Osipiuk, J]]
[[Category: Savchenko, A]]
[[Category: Singer, A U]]
[[Category: Dna-binding]]
[[Category: Mcsg]]
[[Category: PSI, Protein structure initiative]]
[[Category: Transcription regulation]]
[[Category: Transcription regulator]]
[[Category: Transcriptional repressor structure escherichia coli]]