View source for 3doa


==The crystal structure of the fibrinogen binding protein from Staphylococcus aureus==
<StructureSection load='3doa' size='340' side='right'caption='[[3doa]], [[Resolution|resolution]] 2.81&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3doa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_Mu50 Staphylococcus aureus subsp. aureus Mu50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DOA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DOA FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.81&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3doa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3doa OCA], [https://pdbe.org/3doa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3doa RCSB], [https://www.ebi.ac.uk/pdbsum/3doa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3doa ProSAT], [https://www.topsan.org/Proteins/MCSG/3doa TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A0H3JV08_STAAM A0A0H3JV08_STAAM] Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.[HAMAP-Rule:MF_00844]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/do/3doa_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3doa ConSurf].
<div style="clear:both"></div>

==See Also==
*[[Fibrinogen binding protein|Fibrinogen binding protein]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Staphylococcus aureus subsp. aureus Mu50]]
[[Category: Freeman L]]
[[Category: Joachimiak A]]
[[Category: Wu R]]
[[Category: Zhang R]]