View source for 3h80


==Crystal structure of the amino-terminal domain of HSP90 from Leishmania major, LmjF33.0312:M1-K213==
<StructureSection load='3h80' size='340' side='right'caption='[[3h80]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3h80]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_major_strain_Friedlin Leishmania major strain Friedlin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H80 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3H80 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3h80 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3h80 OCA], [https://pdbe.org/3h80 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3h80 RCSB], [https://www.ebi.ac.uk/pdbsum/3h80 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3h80 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q4Q4I6_LEIMA Q4Q4I6_LEIMA] 
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h8/3h80_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3h80 ConSurf].
<div style="clear:both"></div>

==See Also==
*[[Heat Shock Protein structures|Heat Shock Protein structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Leishmania major strain Friedlin]]
[[Category: Arrowsmith CH]]
[[Category: Bochkarev A]]
[[Category: Bountra C]]
[[Category: Cossar D]]
[[Category: Edwards AM]]
[[Category: Fairlamb A]]
[[Category: Ferguson MAJ]]
[[Category: Hills T]]
[[Category: Hui R]]
[[Category: Hutchinson A]]
[[Category: Kozieradzki I]]
[[Category: Lin YH]]
[[Category: Mackenzie F]]
[[Category: Pizarro JC]]
[[Category: Schapira M]]
[[Category: Tempel W]]
[[Category: Weigelt J]]
[[Category: Wernimont AK]]
[[Category: Zhao Y]]