View source for 3j6p


==Pseudo-atomic model of dynein microtubule binding domain-tubulin complex based on a cryoEM map==
<SX load='3j6p' size='340' side='right' viewer='molstar' caption='[[3j6p]], [[Resolution|resolution]] 8.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3j6p]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Dictyostelium_discoideum Dictyostelium discoideum] and [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J6P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3J6P FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 8.2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TA1:TAXOL'>TA1</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3j6p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j6p OCA], [https://pdbe.org/3j6p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3j6p RCSB], [https://www.ebi.ac.uk/pdbsum/3j6p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3j6p ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DYHC_DICDI DYHC_DICDI] Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP.

==See Also==
*[[Dynein 3D structures|Dynein 3D structures]]
*[[Tubulin 3D Structures|Tubulin 3D Structures]]
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</SX>
[[Category: Dictyostelium discoideum]]
[[Category: Large Structures]]
[[Category: Sus scrofa]]
[[Category: Ayukawa R]]
[[Category: Fujii T]]
[[Category: Hachikubo Y]]
[[Category: Kon T]]
[[Category: Kurisu G]]
[[Category: Minoura I]]
[[Category: Muto E]]
[[Category: Namba K]]
[[Category: Nishikawa Y]]
[[Category: Sutoh K]]
[[Category: Takazaki H]]
[[Category: Uchimura S]]