View source for 3j99


==Structure of 20S supercomplex determined by single particle cryoelectron microscopy (State IIIb)==
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== Structural highlights ==
<table><tr><td colspan='2'>[[3j99]] is a 13 chain structure with sequence from [https://en.wikipedia.org/wiki/Cricetulus_griseus Cricetulus griseus] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J99 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3J99 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 8.201&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3j99 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j99 OCA], [https://pdbe.org/3j99 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3j99 RCSB], [https://www.ebi.ac.uk/pdbsum/3j99 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3j99 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NSF_CRIGR NSF_CRIGR] Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seem to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. Interaction with AMPAR subunit GRIA2 leads to influence GRIA2 membrane cycling.

==See Also==
*[[Synaptosomal-associated protein|Synaptosomal-associated protein]]
*[[Syntaxin 3D structures|Syntaxin 3D structures]]
*[[Vesicle-associated membrane protein|Vesicle-associated membrane protein]]
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[[Category: Cricetulus griseus]]
[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Brunger AT]]
[[Category: Cheng Y]]
[[Category: Wu S]]
[[Category: Zhao M]]