View source for 3jco


==Structure of yeast 26S proteasome in M1 state derived from Titan dataset==
<SX load='3jco' size='340' side='right' viewer='molstar' caption='[[3jco]], [[Resolution|resolution]] 4.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3jco]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JCO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JCO FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.8&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jco FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jco OCA], [https://pdbe.org/3jco PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jco RCSB], [https://www.ebi.ac.uk/pdbsum/3jco PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jco ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RPN12_YEAST RPN12_YEAST] Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. Necessary for activation of the CDC28 kinase.
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</SX>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Huang XL]]
[[Category: Luan B]]
[[Category: Shi YG]]
[[Category: Wang F]]
[[Category: Wu JP]]