View source for 3kee


==HCV NS3/NS4A complexed with Non-covalent macrocyclic compound TMC435==
<StructureSection load='3kee' size='340' side='right'caption='[[3kee]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3kee]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepacivirus_C Hepacivirus C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KEE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KEE FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=30B:(2R,3AR,10Z,11AS,12AR,14AR)-N-(CYCLOPROPYLSULFONYL)-2-({7-METHOXY-8-METHYL-2-[4-(1-METHYLETHYL)-1,3-THIAZOL-2-YL]QUINOLIN-4-YL}OXY)-5-METHYL-4,14-DIOXO-2,3,3A,4,5,6,7,8,9,11A,12,13,14,14A-TETRADECAHYDROCYCLOPENTA[C]CYCLOPROPA[G][1,6]DIAZACYCLOTETRADECINE-12A(1H)-CARBOXAMIDE'>30B</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kee FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kee OCA], [https://pdbe.org/3kee PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kee RCSB], [https://www.ebi.ac.uk/pdbsum/3kee PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kee ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/P90191_9HEPC P90191_9HEPC] 

==See Also==
*[[Virus protease 3D structures|Virus protease 3D structures]]
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</StructureSection>
[[Category: Hepacivirus C]]
[[Category: Large Structures]]
[[Category: Cummings MD]]
[[Category: Lindberg JD]]
[[Category: Nystrom S]]