View source for 3kvo


==Crystal structure of the catalytic domain of human Hydroxysteroid dehydrogenase like 2 (HSDL2)==
<StructureSection load='3kvo' size='340' side='right'caption='[[3kvo]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3kvo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KVO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KVO FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kvo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kvo OCA], [https://pdbe.org/3kvo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kvo RCSB], [https://www.ebi.ac.uk/pdbsum/3kvo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kvo ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HSDL2_HUMAN HSDL2_HUMAN] Has apparently no steroid dehydrogenase activity.<ref>PMID:19703561</ref> 
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kv/3kvo_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3kvo ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Arrowsmith CH]]
[[Category: Bhatia C]]
[[Category: Bountra C]]
[[Category: Edwards A]]
[[Category: Huang J]]
[[Category: Kavanagh KL]]
[[Category: Krojer T]]
[[Category: Muniz JRC]]
[[Category: Oppermann U]]
[[Category: Pike ACW]]
[[Category: Pilka E]]
[[Category: Ugochukwu E]]
[[Category: Verdin EM]]
[[Category: Weigelt J]]
[[Category: Von Delft F]]