View source for 3n3y


==Crystal structure of Thymidylate Synthase X (ThyX) from Helicobacter pylori with FAD and dUMP at 2.31A resolution==
<StructureSection load='3n3y' size='340' side='right'caption='[[3n3y]], [[Resolution|resolution]] 2.31&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3n3y]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori_SS1 Helicobacter pylori SS1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N3Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3N3Y FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.307&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3n3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n3y OCA], [https://pdbe.org/3n3y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3n3y RCSB], [https://www.ebi.ac.uk/pdbsum/3n3y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3n3y ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q5UVJ4_HELPX Q5UVJ4_HELPX] Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate.[HAMAP-Rule:MF_01408]

==See Also==
*[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]]
__TOC__
</StructureSection>
[[Category: Helicobacter pylori SS1]]
[[Category: Large Structures]]
[[Category: Chen J]]
[[Category: Chen L]]
[[Category: Jiang H]]
[[Category: Shen X]]
[[Category: Wang K]]
[[Category: Wang Q]]