View source for 3n87


==Crystal structure of 3-dehydroquinate dehydratase from Mycobacterium tuberculosis in complex with inhibitor 3==
<StructureSection load='3n87' size='340' side='right'caption='[[3n87]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3n87]] is a 24 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N87 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3N87 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=N87:(1R,4R,5R)-1,4,5-TRIHYDROXY-3-[3-(PHENYLCARBONYL)PHENYL]CYCLOHEX-2-ENE-1-CARBOXYLIC+ACID'>N87</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3n87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n87 OCA], [https://pdbe.org/3n87 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3n87 RCSB], [https://www.ebi.ac.uk/pdbsum/3n87 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3n87 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/AROQ_MYCTU AROQ_MYCTU] Catalyzes a trans-dehydration via an enolate intermediate (By similarity).[HAMAP-Rule:MF_00169]

==See Also==
*[[Dehydroquinase 3D structures|Dehydroquinase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Abell C]]
[[Category: Blundell TL]]
[[Category: Bromfield KM]]
[[Category: Ciulli A]]
[[Category: Dias MVB]]
[[Category: Howard NI]]
[[Category: Palaninathan SK]]
[[Category: Payne R]]
[[Category: Sacchettini JC]]
[[Category: Snee WC]]