View source for 3olj


==Crystal structure of human ribonucleotide reductase subunit M2 (hRRM2)==
<StructureSection load='3olj' size='340' side='right'caption='[[3olj]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3olj]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OLJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OLJ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3olj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3olj OCA], [https://pdbe.org/3olj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3olj RCSB], [https://www.ebi.ac.uk/pdbsum/3olj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3olj ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RIR2_HUMAN RIR2_HUMAN] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.

==See Also==
*[[Ribonucleotide reductase 3D structures|Ribonucleotide reductase 3D structures]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Chen BE]]
[[Category: Chen XH]]
[[Category: Jiang HJ]]
[[Category: Shao JM]]
[[Category: Xu ZJ]]
[[Category: Yang CG]]
[[Category: Zhu WL]]