View source for 3onr


==Crystal structure of the calcium chelating immunodominant antigen, calcium dodecin (Rv0379),from Mycobacterium tuberculosis with a novel calcium-binding site==
<StructureSection load='3onr' size='340' side='right'caption='[[3onr]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3onr]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ONR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ONR FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=PT:PLATINUM+(II)+ION'>PT</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3onr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3onr OCA], [https://pdbe.org/3onr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3onr RCSB], [https://www.ebi.ac.uk/pdbsum/3onr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3onr ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DODEC_MYCTU DODEC_MYCTU] Binds calcium ions. May play a role in sequestering additional small ligands.<ref>PMID:21370306</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Arulandu A]]
[[Category: Sacchettini JC]]