View source for 3ooy


==Crystal structure of human Transketolase (TKT)==
<StructureSection load='3ooy' size='340' side='right'caption='[[3ooy]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3ooy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OOY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OOY FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=TPP:THIAMINE+DIPHOSPHATE'>TPP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ooy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ooy OCA], [https://pdbe.org/3ooy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ooy RCSB], [https://www.ebi.ac.uk/pdbsum/3ooy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ooy ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TKT_HUMAN TKT_HUMAN] Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.

==See Also==
*[[Transketolase 3D structures|Transketolase 3D structures]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Arrowsmith CH]]
[[Category: Bountra C]]
[[Category: Chaikuad A]]
[[Category: Edwards A]]
[[Category: Guo K]]
[[Category: Kavanagh K]]
[[Category: Kochan G]]
[[Category: Krojer T]]
[[Category: Krysztofinska E]]
[[Category: Oppermann U]]
[[Category: Pilka E]]
[[Category: Vollmar M]]
[[Category: Weigelt J]]
[[Category: Von Delft F]]