View source for 3op0


==Crystal structure of Cbl-c (Cbl-3) TKB domain in complex with EGFR pY1069 peptide==
<StructureSection load='3op0' size='340' side='right'caption='[[3op0]], [[Resolution|resolution]] 2.52&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3op0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OP0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OP0 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.52&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3op0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3op0 OCA], [https://pdbe.org/3op0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3op0 RCSB], [https://www.ebi.ac.uk/pdbsum/3op0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3op0 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CBLC_HUMAN CBLC_HUMAN] Regulator of EGFR mediated signal transduction.
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Arrowsmith CH]]
[[Category: Ayinampudi V]]
[[Category: Bountra C]]
[[Category: Bullock A]]
[[Category: Canning P]]
[[Category: Chaikuad A]]
[[Category: Cooper CDO]]
[[Category: Edwards AM]]
[[Category: Guo K]]
[[Category: Krojer T]]
[[Category: Muniz JRC]]
[[Category: Ugochukwu E]]
[[Category: Vollmar M]]
[[Category: Weigelt J]]
[[Category: Von Delft F]]