View source for 3ovn


==Fragment-based approach to the design of ligands targeting a novel site on HIV-1 integrase==
<StructureSection load='3ovn' size='340' side='right'caption='[[3ovn]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3ovn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OVN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OVN FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=FRU:FRUCTOSE'>FRU</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=MPV:1-METHYL-3-(THIOPHEN-2-YL)-1H-PYRAZOL-5-AMINE'>MPV</scene>, <scene name='pdbligand=PRD_900003:sucrose'>PRD_900003</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ovn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ovn OCA], [https://pdbe.org/3ovn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ovn RCSB], [https://www.ebi.ac.uk/pdbsum/3ovn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ovn ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q72498_9HIV1 Q72498_9HIV1] 
__TOC__
</StructureSection>
[[Category: Human immunodeficiency virus 1]]
[[Category: Large Structures]]
[[Category: Chalmers DK]]
[[Category: Deadman JJ]]
[[Category: Headey SJ]]
[[Category: Parker MW]]
[[Category: Rhodes DK]]
[[Category: Scanlon MJ]]
[[Category: Wielens J]]