View source for 3psp


==Crystal structure of PUL and PFU domain==
<StructureSection load='3psp' size='340' side='right'caption='[[3psp]], [[Resolution|resolution]] 2.42&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3psp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PSP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PSP FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.422&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3psp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3psp OCA], [https://pdbe.org/3psp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3psp RCSB], [https://www.ebi.ac.uk/pdbsum/3psp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3psp ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DOA1_YEAST DOA1_YEAST] Participates in the regulation of the ubiquitin conjugation pathway involving CDC48 by hindering multiubiquitination of substrates at the CDC48 chaperone. May act by preventing the interaction between CDC48 and the E4 enzyme UFD2, leading to prevent multiubiquitination of substrates and subsequent degradation. Essential for maintaining cellular ubiquitin levels.<ref>PMID:15096053</ref> <ref>PMID:8890162</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Liu Y]]
[[Category: Sun J]]