View source for 3pug


==Haloferax volcanii Malate Synthase Native at 3mM Glyoxylate==
<StructureSection load='3pug' size='340' side='right'caption='[[3pug]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3pug]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Haloferax_volcanii_DS2 Haloferax volcanii DS2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PUG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PUG FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GLV:GLYOXYLIC+ACID'>GLV</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pug FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pug OCA], [https://pdbe.org/3pug PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pug RCSB], [https://www.ebi.ac.uk/pdbsum/3pug PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pug ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ACEB_HALVD ACEB_HALVD] Involved in the glyoxylate cycle which synthesizes precursors for carbohydrates from C2 compounds such as acetate. Catalyzes the Claisen condensation between acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form the malyl-CoA intermediate that is subsequently hydrolyzed to produce malate and CoA.<ref>PMID:11513957</ref> <ref>PMID:21569248</ref> <ref>PMID:9738442</ref> 

==See Also==
*[[Malate synthase 3D structures|Malate synthase 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Haloferax volcanii DS2]]
[[Category: Large Structures]]
[[Category: Bracken CD]]
[[Category: Howard BR]]
[[Category: Lamlenn KK]]
[[Category: Neighbor AM]]
[[Category: Schubert HL]]
[[Category: Thomas GC]]
[[Category: Whitby FG]]