View source for 3pvv


==Structure of Mycobacterium tuberculosis DnaA-DBD in complex with box1 DNA==
<StructureSection load='3pvv' size='340' side='right'caption='[[3pvv]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3pvv]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Ra Mycobacterium tuberculosis H37Ra]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PVV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PVV FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pvv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pvv OCA], [https://pdbe.org/3pvv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pvv RCSB], [https://www.ebi.ac.uk/pdbsum/3pvv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pvv ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DNAA_MYCTA DNAA_MYCTA] Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.[HAMAP-Rule:MF_00377]

==See Also==
*[[DnaA|DnaA]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis H37Ra]]
[[Category: Biswas T]]
[[Category: Tsodikov OV]]