View source for 3qj8


==Crystal structure of fatty acid amide hydrolase==
<StructureSection load='3qj8' size='340' side='right'caption='[[3qj8]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3qj8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QJ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QJ8 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qj8 OCA], [https://pdbe.org/3qj8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qj8 RCSB], [https://www.ebi.ac.uk/pdbsum/3qj8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qj8 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FAAH1_RAT FAAH1_RAT] Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes polyunsaturated substrate anandamide preferentially as compared to monounsaturated substrates (By similarity).

==See Also==
*[[Fatty acid amide hydrolase|Fatty acid amide hydrolase]]
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</StructureSection>
[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Min X]]
[[Category: Walker NPC]]
[[Category: Wang Z]]