View source for 3qkw


==Structure of Streptococcus parasangunini Gtf3 glycosyltransferase==
<StructureSection load='3qkw' size='340' side='right'caption='[[3qkw]], [[Resolution|resolution]] 2.29&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3qkw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_parasanguinis Streptococcus parasanguinis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QKW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QKW FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.287&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qkw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qkw OCA], [https://pdbe.org/3qkw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qkw RCSB], [https://www.ebi.ac.uk/pdbsum/3qkw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qkw ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GTF3_STRPA GTF3_STRPA] Required for polymorphic O-glycosylation of the serine-rich repeat protein Fap1. Catalyzes the second step in glycosylation of the serine-rich repeat protein in this bacteria. Transfers glucose from UDP-glucose to the terminal GlcNAc moiety of 3-O-(N-acetyl-alpha-D-glucosaminyl)-L-seryl-[protein] which results from the first glycosylation step of Fap1; does not use other sugar nucleotides as substrates.<ref>PMID:20164186</ref> <ref>PMID:21653318</ref> <ref>PMID:25404702</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Streptococcus parasanguinis]]
[[Category: Ding L]]
[[Category: Erlandsen H]]
[[Category: Huang Y]]
[[Category: Liang X]]
[[Category: Ma J-B]]
[[Category: Wu H]]
[[Category: Zhou M]]
[[Category: Zhu F]]