View source for 3qo6


==Crystal structure analysis of the plant protease Deg1==
<StructureSection load='3qo6' size='340' side='right'caption='[[3qo6]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3qo6]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana] and [https://en.wikipedia.org/wiki/Unidentified Unidentified]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QO6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QO6 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qo6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qo6 OCA], [https://pdbe.org/3qo6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qo6 RCSB], [https://www.ebi.ac.uk/pdbsum/3qo6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qo6 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DEGP1_ARATH DEGP1_ARATH] Serine protease that is required at high temperature. May be involved in the degradation of damaged proteins. In vivo, can degrade beta-casein.
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Deg1 is a chloroplastic protease involved in maintaining the photosynthetic machinery. Structural and biochemical analyses reveal that the inactive Deg1 monomer is transformed into the proteolytically active hexamer at acidic pH. The change in pH is sensed by His244, which upon protonation, repositions a specific helix to trigger oligomerization. This system ensures selective activation of Deg1 during daylight, when acidification of the thylakoid lumen occurs and photosynthetic proteins are damaged.

Structural adaptation of the plant protease Deg1 to repair photosystem II during light exposure.,Kley J, Schmidt B, Boyanov B, Stolt-Bergner PC, Kirk R, Ehrmann M, Knopf RR, Naveh L, Adam Z, Clausen T Nat Struct Mol Biol. 2011 Jun;18(6):728-31. Epub 2011 May 1. PMID:21532594<ref>PMID:21532594</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 3qo6" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Large Structures]]
[[Category: Unidentified]]
[[Category: Clausen T]]