View source for 3qpb


==Crystal Structure of Streptococcus Pyogenes Uridine Phosphorylase Reveals a Subclass of the NP-I Superfamily==
<StructureSection load='3qpb' size='340' side='right'caption='[[3qpb]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3qpb]] is a 18 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pyogenes_serotype_M6 Streptococcus pyogenes serotype M6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QPB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QPB FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.82&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=R1P:RIBOSE-1-PHOSPHATE'>R1P</scene>, <scene name='pdbligand=URA:URACIL'>URA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qpb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qpb OCA], [https://pdbe.org/3qpb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qpb RCSB], [https://www.ebi.ac.uk/pdbsum/3qpb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qpb ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q5XA29_STRP6 Q5XA29_STRP6] Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.[RuleBase:RU361131]

==See Also==
*[[Uridine phosphorylase 3D structures|Uridine phosphorylase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Streptococcus pyogenes serotype M6]]
[[Category: Christoffersen S]]
[[Category: Ealick SE]]
[[Category: Parker WB]]
[[Category: Piskur J]]
[[Category: Serra I]]
[[Category: Terreni M]]
[[Category: Tran TH]]