View source for 3qpl


==G106W mutant of EthR from Mycobacterium tuberculosis==
<StructureSection load='3qpl' size='340' side='right'caption='[[3qpl]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3qpl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QPL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QPL FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qpl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qpl OCA], [https://pdbe.org/3qpl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qpl RCSB], [https://www.ebi.ac.uk/pdbsum/3qpl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qpl ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ETHR_MYCTU ETHR_MYCTU] Involved in the repression of the monooxygenase EthA which is responsible of the formation of the active metabolite of ethionamide (ETH).<ref>PMID:10869356</ref> <ref>PMID:10944230</ref> 

==See Also==
*[[Tetracycline repressor protein 3D structures|Tetracycline repressor protein 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Baulard A]]
[[Category: Carette X]]
[[Category: Deprez B]]
[[Category: Dirie B]]
[[Category: England P]]
[[Category: Frenois F]]
[[Category: Hoos S]]
[[Category: Lecat-Guillet N]]
[[Category: Locht C]]
[[Category: Villeret V]]
[[Category: Willand N]]
[[Category: Willery E]]