View source for 3qs3


==Crystal structure of the biofilm forming subunit of the E. coli common pilus: donor strand complemented (DSC) EcpA==
<StructureSection load='3qs3' size='340' side='right'caption='[[3qs3]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3qs3]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_CFT073 Escherichia coli CFT073]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QS3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QS3 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qs3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qs3 OCA], [https://pdbe.org/3qs3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qs3 RCSB], [https://www.ebi.ac.uk/pdbsum/3qs3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qs3 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ECPD_ECOL6 ECPD_ECOL6] Part of the ecpRABCDE operon, which encodes the E.coli common pilus (ECP). ECP is found in both commensal and pathogenic strains and plays a dual role in early-stage biofilm development and host cell recognition. Tip pilus adhesin, which is required for assembly of EcpA into fibers (By similarity).[https://www.uniprot.org/uniprot/ECPA_ECOL6 ECPA_ECOL6] Part of the ecpRABCDE operon, which encodes the E.coli common pilus (ECP). ECP is found in both commensal and pathogenic strains and plays a dual role in early-stage biofilm development and host cell recognition. Major subunit of the fimbria.<ref>PMID:22355107</ref> 
== References ==
<references/>
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</StructureSection>
[[Category: Escherichia coli CFT073]]
[[Category: Large Structures]]
[[Category: Garnett JA]]
[[Category: Matthews SJ]]