View source for 3qxs


==Crystal structure of dethiobiotin synthetase (BioD) from Helicobacter pylori complexed with ANP==
<StructureSection load='3qxs' size='340' side='right'caption='[[3qxs]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3qxs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori_26695 Helicobacter pylori 26695]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QXS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QXS FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.35&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qxs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qxs OCA], [https://pdbe.org/3qxs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qxs RCSB], [https://www.ebi.ac.uk/pdbsum/3qxs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qxs ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/BIOD_HELPY BIOD_HELPY] Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity).[HAMAP-Rule:MF_00336]

==See Also==
*[[Dethiobiotin synthetase 3D structures|Dethiobiotin synthetase 3D structures]]
__TOC__
</StructureSection>
[[Category: Helicobacter pylori 26695]]
[[Category: Large Structures]]
[[Category: Chruszcz M]]
[[Category: Jablonska K]]
[[Category: Joachimiak A]]
[[Category: Klimecka MM]]
[[Category: Minor W]]
[[Category: Murzyn K]]
[[Category: Porebski PJ]]