View source for 3rjm


==CASPASE2 IN COMPLEX WITH CHDI LIGAND 33c==
<StructureSection load='3rjm' size='340' side='right'caption='[[3rjm]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3rjm]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RJM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RJM FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.55&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3PX:(3S)-3-(PROPAN-2-YLOXY)-L-PROLINE'>3PX</scene>, <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=ASJ:(3S)-3-AMINO-4-HYDROXYBUTANOIC+ACID'>ASJ</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rjm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rjm OCA], [https://pdbe.org/3rjm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rjm RCSB], [https://www.ebi.ac.uk/pdbsum/3rjm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rjm ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CASP2_HUMAN CASP2_HUMAN] Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.

==See Also==
*[[Caspase 3D structures|Caspase 3D structures]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Abendroth J]]
[[Category: Kiselyov AS]]
[[Category: Lorimer D]]
[[Category: Maillard M]]
[[Category: Stewart L]]