View source for 3rpu


==Crystal structure of the MukE-MukF complex==
<StructureSection load='3rpu' size='340' side='right'caption='[[3rpu]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3rpu]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RPU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RPU FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.6&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rpu OCA], [https://pdbe.org/3rpu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rpu RCSB], [https://www.ebi.ac.uk/pdbsum/3rpu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rpu ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MUKF_ECOLI MUKF_ECOLI] Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.<ref>PMID:8602138</ref> 

==See Also==
*[[Condensin|Condensin]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Ghirlando R]]
[[Category: Gloyd M]]
[[Category: Guarne A]]