View source for 3rrd


==Native structure of Dioclea virgata lectin==
<StructureSection load='3rrd' size='340' side='right'caption='[[3rrd]], [[Resolution|resolution]] 2.46&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3rrd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Dioclea_virgata Dioclea virgata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RRD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RRD FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.46&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rrd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rrd OCA], [https://pdbe.org/3rrd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rrd RCSB], [https://www.ebi.ac.uk/pdbsum/3rrd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rrd ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LECA_DIOVI LECA_DIOVI] D-mannose/D-glucose-binding lectin. Has anti-inflammatory activity in rats. Induces histamine release in mast cells from hamster and rat. Induces lymphocyte proliferation and IFNG production. Shows toxicity against the aquatic snail B.glabrata at concentrations higher than 20 ug/ml.[REFERENCE:1]<ref>PMID:1398779</ref> <ref>PMID:7524287</ref> <ref>PMID:8891754</ref> <ref>PMID:18472821</ref> <ref>PMID:9575151</ref> <ref>PMID:10747944</ref> <ref>PMID:19765980</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Dioclea virgata]]
[[Category: Large Structures]]
[[Category: Alencar KL]]
[[Category: Bezerra EHS]]
[[Category: Bezerra MJ]]
[[Category: Cavada BS]]
[[Category: Delatorre P]]
[[Category: Farias DL]]
[[Category: Gadelha CAA]]
[[Category: Nagano CS]]
[[Category: Nobrega RB]]
[[Category: Rocha BAM]]
[[Category: Santi-Gadelha T]]