View source for 3rse


==Structural and biochemical characterization of two binding sites for nucleation promoting factor WASp-VCA on Arp2/3 complex==
<StructureSection load='3rse' size='340' side='right'caption='[[3rse]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3rse]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RSE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RSE FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rse FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rse OCA], [https://pdbe.org/3rse PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rse RCSB], [https://www.ebi.ac.uk/pdbsum/3rse PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rse ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ARP3_BOVIN ARP3_BOVIN] Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament. Plays a role in ciliogenesis (By similarity).

==See Also==
*[[Actin-related protein 3D structures|Actin-related protein 3D structures]]
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</StructureSection>
[[Category: Bos taurus]]
[[Category: Large Structures]]
[[Category: Jurgenson CT]]
[[Category: Nolen BJ]]
[[Category: Pollard TD]]
[[Category: Ti S]]