View source for 3s4o


==Protein Tyrosine Phosphatase (putative) from Leishmania major==
<StructureSection load='3s4o' size='340' side='right'caption='[[3s4o]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3s4o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_major Leishmania major]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S4O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S4O FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=THJ:THIOSULFATE'>THJ</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s4o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s4o OCA], [https://pdbe.org/3s4o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s4o RCSB], [https://www.ebi.ac.uk/pdbsum/3s4o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s4o ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PRL1_LEIMA PRL1_LEIMA] Has protein tyrosine phosphatase activity and may act as a virulence factor to support intracellular survival in host macrophages.<ref>PMID:28507071</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Leishmania major]]
[[Category: Arakaki T]]
[[Category: Merritt EA]]