View source for 3sbw


==Crystal structure of the complex between the extracellular domains of mouse PD-1 mutant and human PD-L1==
<StructureSection load='3sbw' size='340' side='right'caption='[[3sbw]], [[Resolution|resolution]] 2.28&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3sbw]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SBW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SBW FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.28&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sbw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sbw OCA], [https://pdbe.org/3sbw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sbw RCSB], [https://www.ebi.ac.uk/pdbsum/3sbw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sbw ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PDCD1_MOUSE PDCD1_MOUSE] Inhibitory cell surface receptor involved in the regulation of T-cell function during immunity and tolerance. Upon ligand binding, inhibits T-cell effector functions in an antigen-specific manner. Possible cell death inducer, in association with other factors (By similarity).

==See Also==
*[[Cell death protein 3D structures|Cell death protein 3D structures]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Almo SC]]
[[Category: Cao E]]
[[Category: Lazar-Molnar E]]
[[Category: Nathenson SG]]
[[Category: Ramagopal UA]]