View source for 3sgt


==Crystal Structure of E. coli undecaprenyl pyrophosphate synthase in complex with BPH-1299==
<StructureSection load='3sgt' size='340' side='right'caption='[[3sgt]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3sgt]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_O6 Escherichia coli O6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SGT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SGT FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=P09:2-{[4-(3,4-DIMETHYLPHENOXY)PHENYL]CARBAMOYL}BENZOIC+ACID'>P09</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sgt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sgt OCA], [https://pdbe.org/3sgt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sgt RCSB], [https://www.ebi.ac.uk/pdbsum/3sgt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sgt ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/UPPS_ECOL6 UPPS_ECOL6] Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.[HAMAP-Rule:MF_01139]

==See Also==
*[[Undecaprenyl pyrophosphate synthase 3D structures|Undecaprenyl pyrophosphate synthase 3D structures]]
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</StructureSection>
[[Category: Escherichia coli O6]]
[[Category: Large Structures]]
[[Category: Cao R]]
[[Category: Liu Y-L]]
[[Category: Oldfield E]]