View source for 3sgx


==Crystal Structure of E. coli undecaprenyl pyrophosphate synthase in complex with BPH-1100==
<StructureSection load='3sgx' size='340' side='right'caption='[[3sgx]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3sgx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SGX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SGX FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0FW:4-{3-[(BIPHENYL-4-YLCARBONYL)AMINO]PHENOXY}BENZENE-1,2-DICARBOXYLIC+ACID'>0FW</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sgx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sgx OCA], [https://pdbe.org/3sgx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sgx RCSB], [https://www.ebi.ac.uk/pdbsum/3sgx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sgx ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/UPPS_ECOLI UPPS_ECOLI] Generates ditrans,octacis-undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP) and farnesyl diphosphate (FPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.<ref>PMID:12756244</ref> 

==See Also==
*[[Undecaprenyl pyrophosphate synthase 3D structures|Undecaprenyl pyrophosphate synthase 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Cao R]]
[[Category: Liu Y-L]]
[[Category: Oldfield E]]