View source for 3tav


==Crystal structure of a Methionine Aminopeptidase from Mycobacterium abscessus==
<StructureSection load='3tav' size='340' side='right'caption='[[3tav]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3tav]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacteroides_abscessus_ATCC_19977 Mycobacteroides abscessus ATCC 19977]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TAV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TAV FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=LMR:(2S)-2-HYDROXYBUTANEDIOIC+ACID'>LMR</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MLT:D-MALATE'>MLT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tav FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tav OCA], [https://pdbe.org/3tav PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tav RCSB], [https://www.ebi.ac.uk/pdbsum/3tav PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tav ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/B1MGB2_MYCA9 B1MGB2_MYCA9] Removes the N-terminal methionine from nascent proteins.[RuleBase:RU003653]  Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.[HAMAP-Rule:MF_01974]

==See Also==
*[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]]
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</StructureSection>
[[Category: Large Structures]]
[[Category: Mycobacteroides abscessus ATCC 19977]]