View source for 3tde


==Crystal structure of S-adenosylmethionine synthetase Rv1392 from Mycobacterium tuberculosis==
<StructureSection load='3tde' size='340' side='right'caption='[[3tde]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3tde]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TDE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TDE FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tde FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tde OCA], [https://pdbe.org/3tde PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tde RCSB], [https://www.ebi.ac.uk/pdbsum/3tde PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tde ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/METK_MYCTU METK_MYCTU] Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme (By similarity).

==See Also==
*[[S-adenosylmethionine synthetase 3D structures|S-adenosylmethionine synthetase 3D structures]]
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</StructureSection>
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis]]